Complexation of Antibiotics with Transition Metal Ions: A Review

Naresh Chouhan, Milan Hait*, Gourisankar Roymahapatra, Mina Huang, Ben Bin Xu, Zhanhu Guo*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


One of the most significant chemical processes for forming complexes is complexation. Various thermodynamic changes occur during the creation of complexes, which have been examined at various temperatures using various methodologies. The goal of this paper is to provide a general overview of antibiotic-metal ion interactions. How does vary the stability constants and it influences the complex formation. In terms of biological significance, changes in the values of thermodynamic properties like free energy (ΔGo), enthalpy (ΔHo), and entropy (ΔSo­) are far more crucial to the development of complexes. This study is very useful for complexation properties as well as stabilities of antibiotics with metal ions.
Original languageEnglish
JournalES Food & Agroforestry
Early online date23 Feb 2022
Publication statusE-pub ahead of print - 23 Feb 2022


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