Inflammasome lights up in systemic sclerosis

John Henderson, Steven O'Reilly*

*Corresponding author for this work

Research output: Contribution to journalEditorialpeer-review

6 Citations (Scopus)
4 Downloads (Pure)


Systemic sclerosis (SSc) is a pro-fibrotic condition with a poorly understood aetiology. Evidence presented by Artlett et al. in this issue suggests that the microRNA miR-155 is key, with its involvement dependent on the NLRP3 inflammasome. This links epigenetic events with inflammasome signalling in SSc and opens the door to new therapeutic strategies for the treatment of SSc.
Original languageEnglish
Article number205
Number of pages2
JournalArthritis Research & Therapy
Issue number1
Publication statusPublished - 18 Sept 2017


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