Magnitude and pattern of hypertension in the Niger Delta: A Systematic Review and Meta-Analysis of community-based studies

Martinsixtus Ezejimofor, Olalekan Uthman, Yen-Fu Chen, Benedeth Ezejimofor, Aloysius Ezeabasili, Saverio Stranges, Ngianga-Bakwin Kandala

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9 Citations (Scopus)
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Background - Emerging evidence found that health inequality in the Niger Delta region in Nigeria has continued to worsen due to epidemiological and environmental risks transitions. This study aims to provide an up-to-date review and the secular trends of hypertension prevalence in Niger Delta. Methods - We systematically searched databases of MEDLINE, EMBASE, African index Medicus and African Journal online from inception to December 30, 2016 for population–based studies providing prevalence estimates of hypertension in the Niger Delta. Eligible studies were included in a random–effect meta-analysis of prevalence and secular trend. The review was reported according to MOOSE guideline. Results - Overall, 34 eligible studies comprising of data on 32715 participants with mean-age of 38.43±2.0 years were identified and included in the meta-analysis. The pooled result showed that across study settings, the prevalence of hypertension in rural population tended to be higher than those in urban areas, 32.0% (95%, CI 25.13-39.28) versus 24.07% (95%, CI 18.13-30.58), however, the difference did not reach a statistical significant level, (P< 0.183). The overall mean SBP was 130.15 (95%, CI 126.85-133.45) mmHg, and the DBP was 80.72 (95%, CI 78.45-82.95). The estimates also vary significantly in men compared to women; 30.26% (95%, CI 23.76-37.17) versus 22.99% (17.60-28.86), P<0.0001 and among those older than 65 years compared to those aged 45-64 years, and more than 2-fold compared to those between 15-44 years, P<0.001. We also observed a continuous increase in prevalence of hypertension in the region (trend = 0.139, P value = 0.0001), such that for every 10 years increase in participants' mean age, the prevalence of hypertension increases by 10.43% (5.73-15.14), P<0.001 Conclusions - This study found evidence that hypertension is a major public health issue in the Niger Delta communities suggesting a positive relationship between socioecioeconomic and lifetyle factors. Improved surveillance and care, as well as better management of the underlying risk factors, primarily undetected or uncontrolled high blood pressure, remains an important public health priority.
Original languageEnglish
Article number010420
JournalJournal of Global Health
Issue number1
Early online date10 Jun 2018
Publication statusPublished - Jun 2018


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