Multi-drug infusion control using model reference adaptive algorithm

Saleh Enbiya, Alamgir Hossain, Fatima Mahieddine

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    3 Citations (Scopus)


    Control of physiological states such as mean arterial pressure (MAP) has been successfully achieved using single drug by different control algorithms. Multi-drug delivery demonstrates a significantly challenging task as compared to control with a single-drug. Also the patient’s sensitivity to the drugs varies from patient to patient. Therefore, the implementation of adaptive controller is very essential to improve the patient care in order to reduce the workload of healthcare staff and costs. This paper presents the design and implementation of the model reference adaptive controller (MRAC) to regulate mean arterial pressure and cardiac output by administering vasoactive and inotropic drugs that are sodium nitroprusside (SNP) and dopamine (DPM) respectively. The proposed adaptive control model has been implemented, tested and verified to demonstrate its merits and capabilities as compared to the existing research work.
    Original languageEnglish
    Title of host publicationAdvances in intelligent and soft computing
    EditorsM.P. Rocha, J.M. Corchado, Fdez Riverola, A. Valencia
    Place of PublicationLondon
    ISBN (Print)978-3642199134
    Publication statusPublished - 2011
    EventAdvances in intelligent and soft computing -
    Duration: 1 Jan 2011 → …


    ConferenceAdvances in intelligent and soft computing
    Period1/01/11 → …


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