Performance Fatigability Is Not Regulated to A Peripheral Critical Threshold

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The critical threshold hypothesis proposes that performance fatigability during high-intensity exercise is tightly regulated by negative-feedback signals from the active muscles. We propose that performance fatigability is simply dependent on the exercise mode and intensity; the consequent adjustments, in skeletal muscle and the other physiological systems that support exercise, interact to modulate fatigue and determine exercise tolerance.
Original languageEnglish
Pages (from-to)240-246
JournalExercise and Sport Sciences Reviews
Issue number4
Early online date11 Jul 2018
Publication statusPublished - 1 Oct 2018


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