Revolutionizing Prokaryotic Systematics Through Next-Generation Sequencing

Vartul Sangal, Leena Nieminen, Nicholas Tucker, Paul Hoskisson

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

9 Citations (Scopus)


Next-generation sequencing has revolutionized modern research in all life sciences. It has been applied in studying evolution, global transmission and local adaptation of pathogens, microbial ecology, genetics and physiology. In this chapter, we have provided a brief summary of recent advances in sequencing technologies and easy to use bioinformatic tools to analyse sequence data, with a focus on prokaryotic biology. We have emphasized the importance of routinely applying whole genome sequencing in prokaryotic systematics, evolution, genotyping and functional characterization.
Original languageEnglish
Title of host publicationNew Approaches to Prokaryotic Systematics
Place of PublicationLondon
Number of pages327
ISBN (Print)9780128001769
Publication statusPublished - 2014

Publication series

NameMethods in Microbiology
ISSN (Electronic)0580-9517


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