Thrombocytopenia after aortic valve replacement: Comparison Between Sutureless Perceval S Valve and Perimount Magna Ease Bioprosthesis

Syed Saleem Mujtaba*, Simon Ledingham, Asif Raza Shah, Stephan Schueler, Stephen Clark, Thasee Pillay

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)
11 Downloads (Pure)


Introduction: The incidence of postoperative thrombocytopenia after aortic valve replacement (AVR) with the Perceval S Sutureless bioprosthesis remains unclear. The aim of this study was to report thrombocytopenia associated with the use of sutureless AVR.

Methods: The data was collected retrospectively for patients who had isolated AVR with sutureless Perceval S valve (Group A: 72 patients) and was compared with patients who underwent isolated sutured AVR with Perimount Magna Ease Bioprosthesis (Group B: 101 patients) in our institution between June 2014 and January 2017.

Results: Cardiopulmonary bypass and cross-clamp time were significantly shorter in group A. Maximum drop in platelet count was 58% mean (day 2.3) in group A versus 44% mean (day 1.7) in group B (P=0.0001). Absolute platelet count on postoperative day 1-6 in group A was significantly less than in group B (P≤0.05). Platelet count recovered to preoperative value in 44% patients in group B versus only in 26% patients in group A at discharge (P=0.018). Moderate thrombocytopenia occurs more often in group A (41% vs. 26%) (P=0.008) while severe thrombocytopenia (<50 x 109) was observed in 6% in group A but never in group B. Platelets (P=0.007) and packed red blood cells (P=0.009) transfusion was significantly higher in the group A.

Conclusion: The implantation of sutureless Perceval aortic valves was associated with a significant drop in platelet count postoperatively with slow recovery and higher platelets and packed red blood cells transfusion requirements. A prospective randomised trial is needed to confirm our findings.

Original languageEnglish
Pages (from-to)169-175
Number of pages7
JournalBrazilian Journal of Cardiovascular Surgery
Issue number2
Publication statusPublished - 1 Mar 2018


Dive into the research topics of 'Thrombocytopenia after aortic valve replacement: Comparison Between Sutureless Perceval S Valve and Perimount Magna Ease Bioprosthesis'. Together they form a unique fingerprint.

Cite this